2015 - AI - CASE REPORT - ENG - ABSTRACT - Intraoral malignant melanoma: an illus-trative report of two case.

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Atıf İçin Kopyala

Doğan M., Gündoğdu B., Erdem H., Bilen H., Gürsan N., Ceylan O.

ORAL SURGERY, ORAL MEDICINE, ORAL PATHOLOGY, ORAL RADIOLOGY, AND ENDODONTICS, cilt.119, sa.3, ss.207, 2015 (SCI-Expanded)

• Yayın Türü: Makale / Vaka Takdimi
• Cilt numarası: 119 Sayı: 3
• Basım Tarihi: 2015
• Doi Numarası: 10.1016/j.oooo.2014.07.465
• Dergi Adı: ORAL SURGERY, ORAL MEDICINE, ORAL PATHOLOGY, ORAL RADIOLOGY, AND ENDODONTICS
• Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
• Sayfa Sayıları: ss.207
• Atatürk Üniversitesi Adresli: Evet

Özet

Melanomas develop from melanocytes which are derived from the neural crest. Primary oral mucosal melanoma is rare, accounts for 0.5% of all oral cancers. Oral subtype has the worst prognosis compared to other mucosal melanoma. We report an unusual case of oral mucosal melanoma of the gingiva with the main characteristics of an in situ and invasive lesion.

Case1: The 3 mm incisional gingival biopsy was taken from a 23 year-old man. A presumptive clinical diagnosis of odontogenic cyst was made.

Case2: The excisional gingival biopsy was taken from a 42 year-old man.The biopsy was 2,5 x 2cm in diameter and 2 mm elevated from mucosal surface. The histological examination showed a downward streaming and pigmentation in the dermis of the tumor cells. Immunohistochemical studies showed positivity for HMB 45, Melan-A, S-100 marker.

Conclusion: Oral cavity should be examined. A detailed physical examination reveales a malign tumor in the oral cavity.