Akademik Veri Yönetim Sistemi
Turkish Journal of Clinical Research, cilt.1, sa.1, ss.22-29, 2025 (Hakemli Dergi)
Aim: Intracranial hydatid cyst is a rare zoonotic disease that should be considered in the differential diagnosis of intracranial space-occupying lesions in endemic regions. This study aims to evaluate and compare the clinical and radiological characteristics, surgical approaches, and outcomes of patients treated for intracranial hydatid cysts over a 30-year period in a single center. Methods: Fifty patients operated on between 1993 and 2023 were retrospectively evaluated and divided into two cohorts: Group A (1993–2003) and Group B (2003–2023). All patients underwent preoperative neurological and radiological assessment, including CT and MRI. Diagnosis was supported by serological tests and systemic imaging. Surgery was performed using the Dowling technique, and all patients received albendazole treatment pre- and postoperatively. Statistical analysis was conducted using chi-square and Student’s t-tests. Results: The mean age significantly decreased from 32.0 ± 13.6 years (Group A) to 22.3 ± 14.2 years (Group B) (p=0.018). Headache was the most common presenting symptom. In Group B, multiple cysts were observed in 31.3%, and mortality occurred in 12.5%. Radiologically, cysts appeared as well-circumscribed, non-enhancing lesions, typically hypodense on CT and hyperintense on T2-weighted MRI. Two patients had alveolar-type cysts with characteristic findings. Conclusion: Intracranial hydatid cyst remains a significant diagnosis in endemic regions, especially in children and young adults. MRI plays a crucial role in detection. Intact surgical removal using the Dowling technique, combined with albendazole therapy, improves outcomes. Continued public health efforts and early diagnosis remain key to reducing disease burden.
Keywords: Hydatid cyst, intracranial echinococcosis, dowling technique, albendazole, surgical outcomes.