The effect of evening primrose oil (Oenothera biennis) on the level of adiponectin and some biochemical parameters in rats with fructose induced metabolic syndrome

Mert H., İRAK K., Çibuk S., YILDIRIM S., Mert N.

ARCHIVES OF PHYSIOLOGY AND BIOCHEMISTRY, cilt.128, sa.6, ss.1539-1547, 2022 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 128 Sayı: 6
  • Basım Tarihi: 2022
  • Doi Numarası: 10.1080/13813455.2020.1781900
  • Dergi Adı: ARCHIVES OF PHYSIOLOGY AND BIOCHEMISTRY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, BIOSIS, CAB Abstracts, Chemical Abstracts Core, EMBASE, Food Science & Technology Abstracts, MEDLINE, Veterinary Science Database
  • Sayfa Sayıları: ss.1539-1547
  • Anahtar Kelimeler: Metabolic syndrome, fructose, evening primrose oil, adiponectin, oxidant-antioxidant status, INDUCED INSULIN-RESISTANCE, ADIPOSE-SPECIFIC PROTEIN, FATTY LIVER-DISEASE, OXIDATIVE STRESS, CONSUMPTION, EXPRESSION, INFLAMMATION, TISSUE, MODEL, HYPERTENSION
  • Atatürk Üniversitesi Adresli: Evet

Özet

The effect of evening primrose oil on adiponectin level and some biochemical parameters in model of fructose-induced metabolic syndrome were investigated. The rats were divided into 4 groups: control, evening primrose oil, fructose, fructose + evening primrose oil. Body weight, daily feed and water consumptions and systolic blood pressures of animals were measured. At the end of trial, blood samples were taken, livers were excised and histopathological examination was performed. Glucose, uric acid, triglyceride, T.cholesterol, LDL, HDL, VLDL, ALT, AST, ALP, LDH, adiponectin, insulin, IL-6, TNF-alpha, TAC, and TOS levels were analysed. Some analysed parameters and systolic blood pressure of fructose + evening primrose oil group decreased significantly compared to fructose group and adiponectin, TAC, and HDL levels were significantly increased. As conclusion, evening primrose oil can be considered as antioxidant agent by reducing oxidative stress, increasing adiponectin levels and insulin sensitivity, anti-inflammatory properties, exhibiting anti-atherogenic effect by regulating dyslipidemia and systolic blood pressure.