Akademik Veri Yönetim Sistemi
2.Uluslararası Travma Kongresi, Konya, Türkiye, 27 - 30 Kasım 2025, ss.15, (Tam Metin Bildiri)
Objective: This
prospective observational study designed to determine the correlation between
serum copeptin (CPT) quantities measured in patients presenting to the
emergency department with multiple traumas and their hemorrhagic shock stage
and blood-fluid replacement needs.
Methods: Adult
(≥18 years), non-pregnant patients introduced to the emergency department of a
university hospital with multiple traumas between September 2023 and September
2024 were analyzed. A prospective observational and analytical study was
managed. At first admission, CPT levels were measured. Additionally, the
amounts of delivered crystalloids and blood transfusions were listed. Ethics
committee approval was obtained, and participants given informed consent.
Results: Serum CPT
levels were statistically significantly higher in patients with major trauma.
CPT levels increased with the progression of the hemorrhagic shock stage. As
the hemorrhagic shock stage increased, the sum of administered crystalloid
fluids decreased, while the need for blood product transfusion remarkably
increased (p=0.001).
Conclusion: The
findings of the study shoewed a correlation between CPT levels and the severity
of hemorrhagic shock in patients with trauma. Increased CPT levels in the early
phase may designate occult bleeding and assist in risk stratification during
trauma management. CPT appears to be a useful laboratory parameter for
recognize between hemorrhagic shock stages 1 and 2, as well as between stages 1
and 3. It can contribute to clinical evaluation and help guide the need for
blood and blood product monitoring, even in the absence of direct patient
observation.
Keywords:
Copeptin, hemorrhagic shock, trauma, injury severity score, resuscitation,
advanced trauma life support, circulation