Preparation of core-shell magnetic molecularly imprinted polymers for extraction of patulin from juice samples

Zhao M., Shao H., Ma J., Li H., He Y., Wang M., ...Daha Fazla

Journal of Chromatography A, cilt.1615, 2020 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 1615
  • Basım Tarihi: 2020
  • Doi Numarası: 10.1016/j.chroma.2019.460751
  • Dergi Adı: Journal of Chromatography A
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, PASCAL, Analytical Abstracts, Aqualine, Aquatic Science & Fisheries Abstracts (ASFA), BIOSIS, CAB Abstracts, Chimica, Compendex, EMBASE, Environment Index, Food Science & Technology Abstracts, MEDLINE, Pollution Abstracts, Veterinary Science Database
  • Anahtar Kelimeler: Patulin, Magnetic molecularly imprinted polymers, Juice, Magnetic dispersion solid-phase extraction, LC-MS/MS, HPLC-DAD, SOLID-PHASE EXTRACTION, SELECTIVE EXTRACTION, APPLE JUICE
  • Atatürk Üniversitesi Adresli: Evet

Özet

© 2019In this study, a novel magnetic molecularly imprinted polymer (MMIP) was prepared by surface imprinting technology using 2-oxin and 6-HNA as dual virtual templates and 4-vinyl pyridine (4-VP) as the functional monomer for extraction of patulin (PAT) from the surface of magnetic nanoparticles. MMIPs were characterized by fourier transformed infrared (FT-IR) spectroscopy, X-ray diffraction, and vibrating sample magnetometry. The results showed that the molecularly imprinted polymer (MIP) was successfully coupled with magnetic nanoparticles and could be used as a magnetic selective recognition material. Moreover, MMIPs have a greater adsorption capacity for PAT than conventional MIPs. The magnetic dispersion solid-phase extraction procedure was optimized and then combined with liquid chromatography-tandem mass spectrometry (MDSPE-LC-MS/MS) for detection of PAT in juice samples. The method showed excellent analytical performance in terms of linearity (ranged between 0.5 μg L−1 and 100 μg L−1with correlation coefficients (r) higher than 0.999) and limit of detection (LOD) (0.1 μg L−1, S/N = 3). At three spiking concentrations (1, 10, and 50 μg L−1), the mean recoveries were ranged between 79.4% and 97.9% with relative standard deviations (RSDs) < 4.7% (n = 3).