Preparation of core-shell magnetic molecularly imprinted polymers for extraction of patulin from juice samples
Journal of Chromatography A, cilt.1615, 2020 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 1615
- Basım Tarihi: 2020
- Doi Numarası: 10.1016/j.chroma.2019.460751
- Dergi Adı: Journal of Chromatography A
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, PASCAL, Analytical Abstracts, Aqualine, Aquatic Science & Fisheries Abstracts (ASFA), BIOSIS, CAB Abstracts, Chimica, Compendex, EMBASE, Environment Index, Food Science & Technology Abstracts, MEDLINE, Pollution Abstracts, Veterinary Science Database
- Anahtar Kelimeler: Patulin, Magnetic molecularly imprinted polymers, Juice, Magnetic dispersion solid-phase extraction, LC-MS/MS, HPLC-DAD, SOLID-PHASE EXTRACTION, SELECTIVE EXTRACTION, APPLE JUICE
- Atatürk Üniversitesi Adresli: Evet
Özet
© 2019In this study, a novel magnetic molecularly imprinted polymer (MMIP) was prepared by surface imprinting technology using 2-oxin and 6-HNA as dual virtual templates and 4-vinyl pyridine (4-VP) as the functional monomer for extraction of patulin (PAT) from the surface of magnetic nanoparticles. MMIPs were characterized by fourier transformed infrared (FT-IR) spectroscopy, X-ray diffraction, and vibrating sample magnetometry. The results showed that the molecularly imprinted polymer (MIP) was successfully coupled with magnetic nanoparticles and could be used as a magnetic selective recognition material. Moreover, MMIPs have a greater adsorption capacity for PAT than conventional MIPs. The magnetic dispersion solid-phase extraction procedure was optimized and then combined with liquid chromatography-tandem mass spectrometry (MDSPE-LC-MS/MS) for detection of PAT in juice samples. The method showed excellent analytical performance in terms of linearity (ranged between 0.5 μg L−1 and 100 μg L−1with correlation coefficients (r) higher than 0.999) and limit of detection (LOD) (0.1 μg L−1, S/N = 3). At three spiking concentrations (1, 10, and 50 μg L−1), the mean recoveries were ranged between 79.4% and 97.9% with relative standard deviations (RSDs) < 4.7% (n = 3).