Immunohistopathological and Biochemical Study of the Effects of Dead Nettle (Urtica Dioica) Extract on Preventing Liver Lesions Induced by Experimental Aflatoxicosis in Rats

YILDIRIM S., Yener Z.

WEST INDIAN MEDICAL JOURNAL, cilt.67, sa.3, ss.254-261, 2018 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 67 Sayı: 3
  • Basım Tarihi: 2018
  • Doi Numarası: 10.7727/wimj.2016.126
  • Dergi Adı: WEST INDIAN MEDICAL JOURNAL
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.254-261
  • Anahtar Kelimeler: Aflatoxicosis, extract of dead nettle leaf, liver lesions, rat, ROOT EXTRACTS, AFLATOXIN-B1, ANTIOXIDANTS, SERUM, L.
  • Atatürk Üniversitesi Adresli: Evet

Özet

Objective: Aflatoxicosis is a mycotoxicosis infection with an acute or chronic course that forms due to aflatoxins (AFs) in humans and animals. Aflatoxins primarily affect the liver and can lead to histopathological necrosis, fibrosis and hepatocarcinogenesis of the organ. This paper studied the preventive effects of dead nettle leaf (Urtica dioica leaf; UDL) extract on liver lesions that were induced by experimental aflatoxicosis in rats.