Akademik Veri Yönetim Sistemi
Cor et Vasa, cilt.67, sa.4, ss.427-435, 2025 (ESCI, Scopus)
Purpose: The relationship between transthoracic echocardiography (TTE) parameters and the prognosis of patients hospitalized in intensive care with a diagnosis of pneumonia is not well known. This study planned to investigate the relationship between patients’ right ventricular functions (RVF) and clinical outcomes. Materials and methods: It is a retrospective study including patients with pneumonia and normal left ventricular ejection fraction (LVEF) who were followed up in the intensive care unit. The severity scores of the patients, complications, and mortality rates during follow-up and TTE data were compared. Results: One hundred and seven patients were included in the study. Seventy-seven (71.9%) of these patients recovered and were discharged (group 1), and 30 (28.1%) died (group 2). The age distributions (mean ± SD) of group 1 and group 2 patients were 67.71 ± 9.65 and 76.67 ± 8.52, respectively (p <0.001). It did not show statistical significance according to gender distribution (0.357). Parameters indicating decreased RV functions and the presence of increased comorbidities were observed more frequently in patients with adverse clinical outcomes and mortality (p <0.001). As a result of the binary logistic regression analysis performed to model the independent effects of TTE measurements on mortality, it was observed that right ventricular fractional area change (RVFAC), pulmonary artery systolic pressure (sPAP), and inferior vena cava (IVC) variables had independent effects on mortality. Conclusion: In our study, it was observed that TTE measurement results deviated more from normal measurement levels in patients with severe pneumonia and poor prognosis compared to other patients. Also the negative impact of increased comorbidity burden on TTE parameters was also observed. It has been determined that RVFAC, sPAP, and IVC measurements, frequently used in evaluating RVF, it is useful in predicting an increase in mortality rates, in patients followed in intensive care due to pneumonia.