A Meta-Analysis of the Associations Between Prolactin (PRL) Gene Polymorphism and Milk Production Traits in Cattle

Motmain Z., ÖZDEMİR M., EKİNCİ K., Saygili E., Bilgin E.

KAFKAS UNIVERSITESI VETERINER FAKULTESI DERGISI, cilt.28, sa.5, ss.627-631, 2022 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 28 Sayı: 5
  • Basım Tarihi: 2022
  • Doi Numarası: 10.9775/kvfd.2022.27857
  • Dergi Adı: KAFKAS UNIVERSITESI VETERINER FAKULTESI DERGISI
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, CAB Abstracts, EMBASE, Veterinary Science Database, Directory of Open Access Journals, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.627-631
  • Anahtar Kelimeler: PRL gene, Polymorphism, Co-dominant, Meta-analysis, Standardized mean difference, GROWTH-HORMONE, BROWN SWISS, HOLSTEIN, YIELD, FREQUENCY, VARIANTS
  • Atatürk Üniversitesi Adresli: Evet

Özet

The meta-analysis method is used to combine results from many independent studies conducted in a different region or area on a specific subject qualitatively and quantitatively and achieve a consensus. The current meta-analysis was conducted to investigate the association between prolactin gene polymorphism and milk production traits in dairy cattle. The data were collected between 2002 and 2021, and a total of 26 published studies were included in this study. The standardized mean difference (SMD) between genotypes was obtained for statistical evaluation, and to this end, the genetic models (dominant; AA + AB and BB, recessive; AB + BB with AA, co-dominant; AA, BB and AB genotypes) were compared with each other. In the analysis results, cattle with the AB versus BB genotype (SMD=0.289, 95% CI 0.005, 0.573) were found to have a statistically significant higher protein yield in comparison with the AA versus AB and AA versus BB genotypes. The relationships between prolactin gene polymorphism and milk yield, fat yield, fat content, and protein content traits were not found to be statistically significant.