Tricyclic sesquiterpene copaene prevents H2O2-induced neurotoxicity

TÜRKEZ H., TOGAR B., TATAR A.

JOURNAL OF INTERCULTURAL ETHNOPHARMACOLOGY, cilt.3, ss.21-28, 2014 (ESCI) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 3
  • Basım Tarihi: 2014
  • Doi Numarası: 10.5455/jice.20131229104710
  • Dergi Adı: JOURNAL OF INTERCULTURAL ETHNOPHARMACOLOGY
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Directory of Open Access Journals
  • Sayfa Sayıları: ss.21-28
  • Anahtar Kelimeler: Copaene, neuroprotection, H2O2, primary neuron, DNA damage, oxidative stress, in vitro
  • Atatürk Üniversitesi Adresli: Evet

Özet

Aim: Copaene (COP), a tricyclic sesquiterpene, is present in several essential oils of medicinal and aromatic plants and has antioxidant and anticarcinogenic features. But, very little information is known about the effects of COP on oxidative stress induced neurotoxicity.