Effect of anakinra, an interleukin one beta antagonist, on oxidative testicular damage induced in rats with ischemia reperfusion

HİRİK, ERKAN; SÜLEYMAN, BAHADIR; MAMMADOV, RENAD; YAPANOĞLU, Turgut; Cimen, Ferda; Cetin, Nihal; Kurt, NEZAHAT

doi:10.1016/j.androl.2017.03.001

Effect of anakinra, an interleukin one beta antagonist, on oxidative testicular damage induced in rats with ischemia reperfusion

HİRİK E., SÜLEYMAN B., MAMMADOV R., YAPANOĞLU T., Cimen F. K., Cetin N., ...Daha Fazla

REVISTA INTERNACIONAL DE ANDROLOGIA, cilt.16, sa.3, ss.87-94, 2018 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 16 Sayı: 3
Basım Tarihi: 2018
Doi Numarası: 10.1016/j.androl.2017.03.001
Dergi Adı: REVISTA INTERNACIONAL DE ANDROLOGIA
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.87-94
Anahtar Kelimeler: Anakinra, Ischemia/reperfusion, Testes damage, Interleukin-1p, Rat, INJURY, TORSION, TESTES, TORSION/DETORSION, QUERCETIN, TISSUE, MODEL
Atatürk Üniversitesi Adresli: Evet

Özet

Background: It has been reported in the literature that proinflammatory interleukin-1 beta (IL-1(3) is increased in cases of testicular ischemia reperfusion (I/R) damage. This information suggests that anakinra, an IL-1p antagonist, may be effective in testicular I/R damage.