Protective effect of gallic acid against cisplatin-induced ototoxicity in rats

KILIÇ, Korhan; SAKAT, Muhammed; Akdemir, Serkan; YILDIRIM, Serkan; SAĞLAM, Yavuz; AŞKIN, Seda

doi:10.1016/j.bjorl.2018.03.001

Protective effect of gallic acid against cisplatin-induced ototoxicity in rats

KILIÇ K., SAKAT M. S., Akdemir F. N. E., YILDIRIM S., SAĞLAM Y. S., AŞKIN S.

BRAZILIAN JOURNAL OF OTORHINOLARYNGOLOGY, vol.85, no.3, pp.267-274, 2019 (SCI-Expanded, Scopus)

Publication Type: Article / Article
Volume: 85 Issue: 3
Publication Date: 2019
Doi Number: 10.1016/j.bjorl.2018.03.001
Journal Name: BRAZILIAN JOURNAL OF OTORHINOLARYNGOLOGY
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Page Numbers: pp.267-274
Keywords: Cisplatin-induced ototoxicity, Gallic acid, Oxidative stress, DPOAE, WISTAR RATS, CHEMOTHERAPY, REDUCTION, ASSAY
Ataturk University Affiliated: Yes

Abstract

Introduction: Cisplatin is an antineoplastic agent widely used in the treatment of a variety of cancers. Ototoxicity is one of the main side-effects restricting the use of cisplatin.