Comparative efficacy of topical lidocaine, tetracaine, and articaine for post-tonsillectomy pain management in children: a prospective, placebo-controlled study


Mutlu V., Kaya Z.

ACTA OTO-LARYNGOLOGICA, cilt.144, sa.4, ss.320-324, 2024 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 144 Sayı: 4
  • Basım Tarihi: 2024
  • Doi Numarası: 10.1080/00016489.2024.2372298
  • Dergi Adı: ACTA OTO-LARYNGOLOGICA
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, International Bibliography of Social Sciences, Biotechnology Research Abstracts, CAB Abstracts, CINAHL, EMBASE, Linguistics & Language Behavior Abstracts, Veterinary Science Database
  • Sayfa Sayıları: ss.320-324
  • Anahtar Kelimeler: Analgesia, children, local anaesthetic, pain, tonsillectomy
  • Atatürk Üniversitesi Adresli: Evet

Özet

Background: The most important problem in tonsillectomy is pain in the early postoperative period. Objective: We purposed to compare the effects of lidocaine, tetracaine, and articaine application to the peritonsillar bed on post-tonsillectomy pain in children. Methods: The prospective, placebo-controlled study included 80 patients, ages 3-14, who were scheduled for elective tonsillectomy. Patients were randomly divided into four groups. Group 1 received 0.9% NaCl; group 2 received 2% lidocaine; group 3 received 2% tetracaine; and group 4 received 4% articaine to the tonsillary bed for 5 min just after the operation. All patients were evaluated in terms of pain and pain-related adverse events in the postoperative 24 h. Results: All groups that used local anesthetics had significantly lower pain levels than the control group in the first eight hours (p < .001). Furthermore, the articaine group had a lower pain score than the tetracaine group at the eighth hour (p < .05). The articaine group had a lower pain score at the 16th hour than both the control and tetracaine groups (p < .05). There was no significant difference between the groups at the 24th hour (p > .05). Conclusion and significance: We recommend the immediate application of topical articaine to the tonsillar bed following the procedure to enhance postoperative pain management.