Akademik Veri Yönetim Sistemi
Agri, cilt.10, sa.4, ss.38-42, 1998 (SCI-Expanded)
Tramadol not only interacts with opioid preceptors, but also inhibits the withdrawal of noradrenaline and seratonin in central nervous system. There are evidences showing the existence of local opioid receptors in sinovia of patients who have undergone arthroscopic knee surgery. In our study, we compared tramadol and morphine for postarthroscopic analgesia. The study was performed on 60 cases going under arthroscopic knee surgery electively under general anesthesia, whose ASA physical status were I-II. At the end of the surgery, before the removal of arthroscope from the intraarticular cavity, the cases were administered, 50 mg tramadol (Group T, n=20) or 5 mg morphine hydrochlorur (HCl) (Group M, n=20) diluted with 10 ml serum physiologic or only 10 ml SF (Group SF, n=20) intraarticularly in a randomized fashion. In the recovery rooom, VAS values were recorded at rest and during flexion of the knee at the 2nd, 4th, 6th, 8th, 12th and 24th hours postoperatively. The first postoperative analgesic requirement durations and the total analgesic comsumptions for the first 24 hours were recorded. Statistical analysis of the data were performed with Mann-Whitney U, X2 and the student's t tests. In the recovery room, the pain scores at the 2nd, 4th and 6th hours postoperatively; at rest and during flexion, and the analgesic consumptions for the 24 hours were lower in group T and M than those of group SF (p<0.0001). In this regard, there was a statistical significant difference between group M and T (p<0.05). As a result, it was determined that tramadol administered intraarticularly after arthroscopic knee surgery is effective in postoperative analgesia in arthroscopy however, intraarticular morphine administration produces superior analgesia.