Thymectomy in Myasthenia Gravis

AYDIN Y., ULAŞ A. B., MUTLU V., ÇOLAK A., EROĞLU A.

EURASIAN JOURNAL OF MEDICINE, cilt.49, ss.48-52, 2017 (ESCI) identifier identifier identifier

  • Yayın Türü: Makale / Derleme
  • Cilt numarası: 49
  • Basım Tarihi: 2017
  • Doi Numarası: 10.5152/eurasianjmed.2017.17009
  • Dergi Adı: EURASIAN JOURNAL OF MEDICINE
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.48-52
  • Anahtar Kelimeler: Extended thymectomy, follow-up, myasthenia gravis, thoracoscopic thymectomy, EXTENDED TRANSCERVICAL THYMECTOMY, ROBOTIC THYMECTOMY, PREDICTIVE FACTORS, PROGNOSTIC-FACTORS, THORACOSCOPIC THYMECTOMY, CRISIS, OUTCOMES, THYMOMA, PLASMAPHERESIS, MANAGEMENT
  • Atatürk Üniversitesi Adresli: Evet

Özet

In recent years, thymectomy has become a widespread procedure in the treatment of myasthenia gravis (MG). Likelihood of remission was highest in preoperative mild disease classification (Osserman classification 1, 2A). In absence of thymoma or hyperplasia, there was no relationship between age and gender in remission with thymectomy. In MG treatment, randomized trials that compare conservative treatment with thymectomy have started, recently. As with non-randomized trials, remission with thymectomy in MG treatment was better than conservative treatment with only medication. There are four major methods for the surgical approach: transcervical, minimally invasive, transsternal, and combined transcervical transsternal thymectomy. Transsternal approach with thymectomy is the accepted standard surgical approach for many years. In recent years, the incidence of thymectomy has been increasing with minimally invasive techniques using thoracoscopic and robotic methods. There are not any randomized, controlled studies which are comparing surgical techniques. However, when comparing non-randomized trials, it is seen that minimally invasive thymectomy approaches give similar results to more aggressive approaches.