Serum 25-Hydroxyvitamin D Level Is Associated With Arterial Stiffness, Left Ventricle Hypertrophy, and Inflammation in Newly Diagnosed Hypertension

Kuloglu, Osman; Gur, Mustafa; Seker, Taner; Kalkan, Gulhan; Sahin, Durmus; TANBOĞA, İbrahim; Koyunsever, Nermin; Harbalioglu, Hazar; Turkoglu, Caner; Akyol, Selahattin; Elbasan, Zafer; Acele, Armagan; Cayli, Murat

doi:10.2310/jim.0b013e31829a82bc

Serum 25-Hydroxyvitamin D Level Is Associated With Arterial Stiffness, Left Ventricle Hypertrophy, and Inflammation in Newly Diagnosed Hypertension

Kuloglu O., Gur M., Seker T., Kalkan G. Y., Sahin D. Y., TANBOĞA İ. H., ...Daha Fazla

JOURNAL OF INVESTIGATIVE MEDICINE, cilt.61, sa.6, ss.989-994, 2013 (SCI-Expanded)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 61 Sayı: 6
Basım Tarihi: 2013
Doi Numarası: 10.2310/jim.0b013e31829a82bc
Dergi Adı: JOURNAL OF INVESTIGATIVE MEDICINE
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.989-994
Atatürk Üniversitesi Adresli: Evet

Özet

Objectives: Vitamin D may modulate vascular inflammation, vascular smooth muscle cell proliferation, the renin-angiotensin system, and cardiomyocyte proliferation, myocardial fibrosis, and proliferation. These mechanisms may play a role on arterial stiffness and left ventricle hypertrophy (LVH) in hypertensive patients. We aimed to evaluate the association between serum vitamin D with arterial stiffness and LVH in patients with hypertension.