The effects of n-butanol on oxidative stress and apoptosis in zebra fish (Danio rerio) larvae

Kokturk M., ALAK G., Atarnanalp M.

COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY, cilt.227, 2020 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 227
  • Basım Tarihi: 2020
  • Doi Numarası: 10.1016/j.cbpc.2019.108636
  • Dergi Adı: COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, Animal Behavior Abstracts, Aquatic Science & Fisheries Abstracts (ASFA), BIOSIS, CAB Abstracts, EMBASE, MEDLINE, Veterinary Science Database
  • Anahtar Kelimeler: N-butanol, Zebrafish, Apoptosis, Acetylcholinesterase, ROS, Oxidative stress, KEEPING NEURONS ALIVE, ETHANOL EXPOSURE, SONIC HEDGEHOG, SUPEROXIDE-DISMUTASE, MOLECULAR CONTROL, RAT, FOREBRAIN, SYSTEM, BRAIN, PEROXIDATION
  • Atatürk Üniversitesi Adresli: Evet

Özet

In recent years, n-butanol has growing use in many areas, including the food industry. In this study, acute toxic effects of n-butanol to zebrafish (Danio rerio) larvae by applying different concentrations (10, 50, 250, 500, 750, 1000 and 1250 mg/L) to embryos were evaluated. For this purpose the data of oxidative stress, antioxidant acetyl cholinesterase enzyme activities, malondialdehyde level and apoptosis were taken into consideration.