Recent advances in bio-supported catalysis based on chitosan: A green platform for efficient Sonogashira reaction
Journal of Organometallic Chemistry, vol.1058, 2026 (SCI-Expanded, Scopus)
- Publication Type: Article / Review
- Volume: 1058
- Publication Date: 2026
- Doi Number: 10.1016/j.jorganchem.2026.124237
- Journal Name: Journal of Organometallic Chemistry
- Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Chemical Abstracts Core, Chimica, Compendex, Academic Search Ultimate (EBSCO), Engineering Source (EBSCO)
- Keywords: Sonogashira reaction, Terminal alkynes, Aryl halides, Chitosan, Bio-supported catalysis
- Ataturk University Affiliated: Yes
Abstract
Organic synthesis is vital to upholding the tenets of green chemistry, as it reduces waste generation, leverages inexpensive, abundant starting materials, and supports the use of reusable catalysts. Lately, catalysis derived from biological sources has gained traction as a viable approach, thanks to its minimal ecological footprint, lower toxicity, and cost-effectiveness. Chitosan and its derivatives, in particular, stand out among bio-based materials for their robust promise as eco-friendly catalytic supports. Chitosan continues to attract significant interest owing to its unique properties and broad potential applications. Each year, publications and patents on this polymer show steady growth, reflecting increasing research momentum. This review article outlines the latest advancements and noteworthy developments (2020–2025) in the usage of chitosan and its derivatives as bio-based supports for metal immobilization in Sonogashira reactions. It covers methodologies for immobilizing metal nanoparticles (Pd, Au, Cu, Ti, and Co) or metal ions on unmodified chitosan, chitosan blended with organic and inorganic polymers, and ligand-functionalized chitosan variants.