Sedative, anticonvulsant and behaviour modifying effects of Centranthus longiflorus ssp longiflorus: a study of comparison to diazepam

BUYUKOKUROGLU M., DEMIREZER L., Guvenalp Z.

PHARMAZIE, cilt.57, sa.8, ss.559-561, 2002 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 57 Sayı: 8
  • Basım Tarihi: 2002
  • Dergi Adı: PHARMAZIE
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.559-561
  • Atatürk Üniversitesi Adresli: Evet

Özet

The aqueous extract of Centranthus longiflorus ssp. longiflorus (CLE) was investigated for sedative, anticonvulsant and behaviour modifying activity using thiopental sleeping, caffeine induced convulsion and forced swimming depression tests. When the effects of the aqueous extract of CLE (100 mg/kg) was compared to diazepam, it showed similar sedative and anticonvulsant effects to those produced by diazepam (5 mg/kg).