Influence of alpha lipoic acid on epithelial apoptosis in experimental periodontitis

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KARA A., Akman S., DEMİRCİ T., ARABACI T., ÇANAKÇI V., ÜNAL B.

TURKISH JOURNAL OF MEDICAL SCIENCES, cilt.43, sa.5, ss.747-755, 2013 (SCI-Expanded)

• Yayın Türü: Makale / Tam Makale
• Cilt numarası: 43 Sayı: 5
• Basım Tarihi: 2013
• Doi Numarası: 10.3906/sag-1208-12
• Dergi Adı: TURKISH JOURNAL OF MEDICAL SCIENCES
• Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
• Sayfa Sayıları: ss.747-755
• Anahtar Kelimeler: Experimental periodontitis, apoptosis, alpha lipoic acid, oxidative stress, ENDOTHELIAL GROWTH-FACTOR, VITAMIN-C, IN-VITRO, EXPRESSION, P53, ANTIOXIDANTS, LYMPHOCYTES, LESIONS, CELLS, PCNA
• Atatürk Üniversitesi Adresli: Evet

Özet

Aim: Alpha lipoic acid (ALA) is a powerful antioxidant. Its antiinflammatory effects and apoptotic mechanism have recently been studied in many diseases. This study aimed to investigate the effects of ALA on apoptotic activity in the treatment of periodontitis.