Potential Anticancer Effect of Carvacrol Codrugs on Human Glioblastoma Cells.

Yazici A., Marinelli L., Cacciatore I., Emsen B., Eusepi P., Di Biase G., ...Daha Fazla

Current drug delivery, cilt.18, ss.349-355, 2021 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 18
  • Basım Tarihi: 2021
  • Doi Numarası: 10.2174/1567201817666201027123424
  • Dergi Adı: Current drug delivery
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, BIOSIS, Biotechnology Research Abstracts, Chemical Abstracts Core, EMBASE, MEDLINE
  • Sayfa Sayıları: ss.349-355
  • Anahtar Kelimeler: Anti-proliferative action, codrug strategy, carvacrol codrug, glioblastoma multiforme, gene expression, DERIVATIVES, PATHWAY, AGENTS, ACID
  • Atatürk Üniversitesi Adresli: Evet

Özet

Background: Essential oils are considered as promising sources of novel anticancer compounds. Carvacrol (CVC), the major constituent of many aromatic plants including oregano and thymus, is endowed with curative properties on different cancers, including liver, colon, and lung. Little information is available regarding the potential of CVC for the treatment of brain cancers, notably Glioblastoma Multiforme (GBM).