MITOCHONDRIAL DNA COPY NUMBER IS ASSOCIATED WITH ATTENTION DEFICIT HYPERACTIVITY DISORDER

Ogutlu H., ESİN İ. S., Erdem H. B., TATAR A., Dursun O. B.

PSYCHIATRIA DANUBINA, cilt.32, sa.2, ss.168-175, 2020 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 32 Sayı: 2
  • Basım Tarihi: 2020
  • Doi Numarası: 10.24869/psyd.2020.168
  • Dergi Adı: PSYCHIATRIA DANUBINA
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Social Sciences Citation Index (SSCI), Scopus, EMBASE, MEDLINE, Psycinfo, Social services abstracts
  • Sayfa Sayıları: ss.168-175
  • Atatürk Üniversitesi Adresli: Evet

Özet

Background: Attention deficit hyperactivity disorder (ADHD) is the most common psychiatric disorder in children. Several hypotheses have been proposed to explain its etiology. Mitochondrial dysfunction (MD) is suggested to be one of the causes of Attention Deficit Hyperactivity Disorder. The objective of the study was to evaluate the relationship between MD and ADHD by investigating mitochondrial DNA (mtDNA) levels from peripheral blood leukocytes, one of the best biomarkers of mitochondrial dysfunction.