Comparison of Mycobacterium Growth Indicator Tube Method and Method of Proportion for Drug Susceptibility of Mycobacterium tuberculosis


AKTAŞ A. E., YİGİT N., AHMET a., BAŞTOPÇU A.

The Aurasian Journal of Medicine, 2014 (Hakemli Dergi) identifier identifier identifier

Özet

Objective: Tuberculosis is an important public health problem in developed and, especially, developing countries. The incidence of multidrug- resistant Mycobacterium tuberculosis (MDR-TB) has increased in recent years. Mycobacterial culture and susceptibility testing must be rapidly concluded for effective treatment and control of the disease. The present study evaluated the reliability of the Mycobacterium Growth Indicator Tube (MGIT) method for testing the susceptibility of M. tuberculosis to four first-line antimicrobial drugs by comparing MGIT results to those obtained by the method of proportion (MOP), which served as the reference method.