Oxidative stress and mRNA expression of acetylcholinesterase in the leukocytes of ischemic patients

Isik M., Beydemir S., YILMAZ A., NALDAN M. E., ASLAN H. E., GÜLÇİN İ.

BIOMEDICINE & PHARMACOTHERAPY, cilt.87, ss.561-567, 2017 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 87
  • Basım Tarihi: 2017
  • Doi Numarası: 10.1016/j.biopha.2017.01.003
  • Dergi Adı: BIOMEDICINE & PHARMACOTHERAPY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.561-567
  • Anahtar Kelimeler: Gene expression, Ischemic stroke, Oxidative stress, Free radical, Acetylcholinesterase, GLUTATHIONE-S-TRANSFERASE, ALZHEIMERS-DISEASE, PROTEIN OXIDATION, STROKE, THERAPY, BRAIN, DIFFERENTIATION, REPERFUSION, BIOMARKERS, SYSTEM
  • Atatürk Üniversitesi Adresli: Evet

Özet

Background: Pathogenesis of ischemic brain injury is occurred by crucial metabolic reasons. For instance, oxidative stress from free radical generation is causing to the thrombotic cerebrovascular stroke. In this case, the measurement of the oxidative stress is very important for a better understanding of the stroke pathophysiology. Because, the oxidative stress in stroke is generally assumed as one of the mechanisms taking part in neuronal damage. Thus, oxidative stress has a vital role in the cholinergic system.