Investigation of Hepatitis B Virus (HBsAg, Anti-HBs) and Anti-Hepatitis C Virus Serology in Erzurum Region: 2015-2023


Uçar M., YILMAZ A., ÇELEBİ D., ÇELEBİ Ö.

Eurasian Journal of Medicine, cilt.57, sa.1, 2025 (ESCI, Scopus, TRDizin) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 57 Sayı: 1
  • Basım Tarihi: 2025
  • Doi Numarası: 10.5152/eurasianjmed.2025.24635
  • Dergi Adı: Eurasian Journal of Medicine
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus, Academic Search Premier, CINAHL, Directory of Open Access Journals, TR DİZİN (ULAKBİM)
  • Anahtar Kelimeler: anti-HBs, anti-HCV, HBsAg, hepatitis, prevalence, serology
  • Atatürk Üniversitesi Adresli: Evet

Özet

Background: Hepatitis B virus (HBV) and hepatitis C virus (HCV) infections are among the problems affect-ing public health worldwide. In this study, we aimed to retrospectively examine the results of patients whose hepatitis B (hepatitis B surface antigen (HBsAg), anti-HBs (Hepatitis B surface antibody) and hepatitis C serology were analyzed by family physicians in the provincial center of Erzurum and to investigate the change in seroprevalence by gender, age groups, and years. Methods: The serology results of individuals whose HBV and anti-HCV serology were analyzed by family physicians in Erzurum between 2015-2023 were evaluated retrospectively. Hepatitis B virus and anti-HCV analyses of the patients were performed in the Public Health Microbiology Laboratory using the chemilu-minescence enzyme immunoassay method in accordance with the study procedure of the producing com-pany. These records of the patients were obtained from the laboratory automation system with permission obtained from the Health Directorate. Results: Our study’s population consisted of 150 862 people. The study determined that HBsAg, anti-HBs, and anti-HCV seropositivity rates were 1.7%, 58.0%, and 0.02%, respectively. The difference between HBsAg and anti-HBs seropositivity results was statistically significant between individuals born before 1998 and those born after 1998. Conclusion: In our study, it is significant that the HBsAg positivity rate tends to decrease, and anti-HBs sero-positivity has been observed at higher rates in recent years. The rate of anti-HCV seropositivity was found to be lower compared to other studies conducted in our region.