Kafkas Universitesi Veteriner Fakultesi Dergisi, cilt.22, ss.801-803, 2016 (SCI-Expanded)
This study was aimed to determine the effects of intramuscular Xylazine HCl administration on intraocular pressure (IOP) in rabbits at 5 mg/kg (XYL-5) and 10 mg/kg (XYL-10) doses. IOP measurements were recorded at baseline (T-(1)), and at 5 (T-5), 10 (T-10), 15 (T-15), 20 (T-20), 30 (T-30), 45 (T-45) and 60 (T-60) minutes following Xylazine HCl administration. IOP values were significantly decreased at T-15 in group XYL-5 (8.37 +/- 1.45 mm Hg) and at T-5 in group XYL-10 (8.00 +/- 1.13 mm Hg). In conclusion, intramuscular Xylazine HCl significantly reduced IOP in rabbits at the latest after 15 minutes of administration, regardless of the doses used in this study.