Akademik Veri Yönetim Sistemi
5 th INTERNATIONAL CONFERENCE ONENGINEERING NATURAL SCIENCES, Van, Türkiye, 20 - 22 Aralık 2019
Hydrogen peroxide (H2O2) plays an important role in biological system as an oxidative stress marker and defense agent. H2O2 is also one of the by-products of several high reagents polluting the environment and serves a critical role in a number normal cell function of neurological disease states. Human body can cause various diseases such as diabetes, cancer, and neurodegenerative disorders with the damage of several classes of essential proteins by H2O2. Therefore, when it reaches high concentrations, it forms a toxic effect on the cell by forming degradation of proteins, lipids and nucleic acids. Furthermore, International Agency for Research on Cancer (IARC) reported that H2O2 is not classified as carcinogenic compound for humans but some mutagenic properties has been observed in in-vitro systems. Cancer-causing effects of H2O2 are currently being investigated by researchers. Thus, H2O2 detection is really important in biological system. Several methods have been investigated for the determination of H2O2 in the literature such as electrochemical, fluorescence, chromatographic. For these methods electrochemistry is the most useful because of its various advantage such as low cost, high sensitivity, low detection limit and allowing to real-time sensing. To increase catalytic activities for detection of H2O2, metal oxides (CuO, PbO, ZnO, TiO2, SnO2 etc.) and metal nanoparticles (Ru, Au, Ag, Pt, etc.) based electrochemical sensors have been frequently studied in the past. Also because of unique nanostructure and an excellent electronic conductivity, graphene based electrochemical sensors have been used for detection of H2O2.
In this study, we report one-pot electrochemical deposition of metal-graphene nanocomposite on Au electrode by one-pot an done-step electrochemical deposition technique using one aqueous solution including metal ions (Pd+2, Cu2+, Ni+2) and graphene oxide. The as-prepared electrode was used for the amperometric detections of H2O2. The results indicate that metal-graphene nanocomposite modified Au electrodes are useful catalysts for the detection of H2O2.