New Chalcone Derivatives with Pyrazole and Sulfonamide Pharmacophores as Carbonic Anhydrase Inhibitors
LETTERS IN DRUG DESIGN & DISCOVERY, cilt.18, sa.2, ss.191-198, 2021 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 18 Sayı: 2
- Basım Tarihi: 2021
- Doi Numarası: 10.2174/1570180817999201001160414
- Dergi Adı: LETTERS IN DRUG DESIGN & DISCOVERY
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Biotechnology Research Abstracts, Chemical Abstracts Core, EMBASE
- Sayfa Sayıları: ss.191-198
- Anahtar Kelimeler: Pyrazoline, sulfonamides, chalcone, carbonic anhydrase isoenzymes, IC50, synthesis, BIOLOGICAL EVALUATION, IX, ANTIFUNGAL, DESIGN
- Atatürk Üniversitesi Adresli: Evet
Özet
Background: Compound containing sulfonamide, pyrazole and chalcone groups are important in medicinal chemistry. They have a wide range of biological activities, including carbonic anhydrase (CA) inhibitory activities.