New Chalcone Derivatives with Pyrazole and Sulfonamide Pharmacophores as Carbonic Anhydrase Inhibitors

TUĞRAK M., GÜL H. İ., Akincioglu H., GÜLÇİN İ.

LETTERS IN DRUG DESIGN & DISCOVERY, cilt.18, sa.2, ss.191-198, 2021 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 18 Sayı: 2
  • Basım Tarihi: 2021
  • Doi Numarası: 10.2174/1570180817999201001160414
  • Dergi Adı: LETTERS IN DRUG DESIGN & DISCOVERY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Biotechnology Research Abstracts, Chemical Abstracts Core, EMBASE
  • Sayfa Sayıları: ss.191-198
  • Anahtar Kelimeler: Pyrazoline, sulfonamides, chalcone, carbonic anhydrase isoenzymes, IC50, synthesis, BIOLOGICAL EVALUATION, IX, ANTIFUNGAL, DESIGN
  • Atatürk Üniversitesi Adresli: Evet

Özet

Background: Compound containing sulfonamide, pyrazole and chalcone groups are important in medicinal chemistry. They have a wide range of biological activities, including carbonic anhydrase (CA) inhibitory activities.