The Protective Roles of Butein on Indomethacin Induced Gastric Ulcer in Mice

UĞAN R. A., ÜN H.

EURASIAN JOURNAL OF MEDICINE, cilt.52, sa.3, ss.265-270, 2020 (ESCI) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 52 Sayı: 3
  • Basım Tarihi: 2020
  • Doi Numarası: 10.5152/eurasianjmed.2020.20022
  • Dergi Adı: EURASIAN JOURNAL OF MEDICINE
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus, Academic Search Premier, CINAHL, Directory of Open Access Journals, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.265-270
  • Anahtar Kelimeler: Butein, ulcer, mice, indomethacin, RHUS-VERNICIFLUA STOKES, ANTIOXIDANT ACTIVITY, INDUCED EXPRESSION, NITRIC-OXIDE, INHIBITION, LIPOXYGENASE, FLAVONOIDS, GENERATION, QUERCETIN, EXTRACT
  • Atatürk Üniversitesi Adresli: Evet

Özet

Objective: Butein is a potential agent first isolated from Rhus verniciflua that has medicinal value in East Asia and has been used in the treatment of gastritis, gastric cancer, and atherosclerosis since ancient times. The aim of our study is to show, for the first time, the anti-ulcerative effect of butein in indomethacin induced gastric ulcer in mice.