Hydroxychloroquine-induced hyperpigmentation: a case report

MELİKOĞLU M., MELİKOĞLU M., Gurbuz U., Budak B. S., KACAR C.

JOURNAL OF CLINICAL PHARMACY AND THERAPEUTICS, cilt.33, sa.6, ss.699-701, 2008 (SCI-Expanded, Scopus)

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 33 Sayı: 6
  • Basım Tarihi: 2008
  • Doi Numarası: 10.1111/j.1365-2710.2008.00955.x
  • Dergi Adı: JOURNAL OF CLINICAL PHARMACY AND THERAPEUTICS
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.699-701
  • Anahtar Kelimeler: antimalarials, hydroxychloroquine, hyperpigmentation, CUTANEOUS HYPERPIGMENTATION, ANTIMALARIAL THERAPY, PIGMENTATION, LUPUS
  • Atatürk Üniversitesi Adresli: Evet

Özet

The antimalarials are one of the most commonly prescribed drugs in medical practice, for conditions such as rheumatoid arthritis as well as malaria. They are generally well-tolerated and the possible side effects of synthetic antimalarials, though infrequent, are well known. Besides the familiar adverse reactions, a localized mucocutaneous bluish-grey to black discolouration can sometimes be seen with antimalarial drugs. The aim of this report was to draw attention to the localized mucocutaneous bluish-grey hyperpigmentation induced by hydroxychloroquine with a case presentation and a review of the literature.