Akademik Veri Yönetim Sistemi
JOURNAL OF CARDIOTHORACIC SURGERY, cilt.19, sa.1, ss.1-7, 2024 (SCI-Expanded)
Abstract
Background The results of the use of del-Nido(DN) solution using a different method or crystalloid blood
cardioplegia in coronary bypass patients were compared. We aimed to investigate the effects on intraoperative and
postoperative arrhythmias, arrhythmia durations and early results.
Methods The study included 175 patients using crystalloid blood cardioplegia (Group 1) and 150 patients using DN
solution(Group 2). In the DN group, 75% of the calculated plegia dose was given first. the remaining part was applied
by giving from grafts. Intraoperative/postoperative data were compared.
Results There was no significant difference between the groups in terms of demographic characteristics. Preop
troponin level was similar.(p=0.190) However, there was a statistical difference between the postoperative 6th hour.
(p=0.001) There was no difference in troponin values at the postoperative 24th hour. (p=0.631) Spontaneous rhythm
occurred at the cardiopulmonary by pass (CPB) weaning stage in most of the patients in Group 2 (95.3%). Although
the need for temporary pacing was less in Group 2, it was not significant.(p=0.282) No patient required permanent
pacing. CPB duration, cross clamp times and intraoperative glucose levels, intensive care follow-up times and
hospitalization times were found to be shorter in Group 2. Although the postoperative atrial fibrillation frequency was
similar (p=0.261), the time to return to sinus was lower in Group 2.(p=0.001).
Conclusion The use of DN cardioplegia solution provides significant positive contributions to avoid arrhythmias
compared to crystalloid blood cardioplegia. DN solution applied with this method may contribute to reducing the
anxieties associated with its use in isolated coronary artery bypass surgery.
Keywords Del nido cardioplegia, Arrhythmia, Coronary artery bypass surgery