Naphthoquinones from the roots of Onosma argentatum Hub.-Mor. (Boraginaceae)
TURKISH JOURNAL OF CHEMISTRY, cilt.28, sa.4, ss.451-454, 2004 (SCI-Expanded, Scopus, TRDizin)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 28 Sayı: 4
- Basım Tarihi: 2004
- Dergi Adı: TURKISH JOURNAL OF CHEMISTRY
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
- Sayfa Sayıları: ss.451-454
- Anahtar Kelimeler: Onosma argentatum, natural naphthoquinones, shikonin derivatives, Boraginaccae, 5,8-O-dimethyl acetyl shikonin, ANTIMICROBIAL ACTIVITIES, PYRROLIZIDINE ALKALOIDS, DERIVATIVES
- Atatürk Üniversitesi Adresli: Evet
Özet
Onosma argentatum Hub.-Mor. is an endemic species growing in Turkey. In this study, the roots of O. argentatum were extracted with n-hexane-dichloromethane (1:1). The extract was separated on a silica gel column eluting with n-hexane-ethyl acetate by gradient elution. New naphthoquinone compounds (3 known and 1 new) were isolated and their structures were elucidated by spectroscopic methods as deoxyshikonin, acetyl shikonin, 3-hydroxy-isovaleryl shikonin, and 5,8-O-dimethyl acetyl shikonin.