Simultaneous Hydrodistillation of Cedrus atlantica Manetti and Salvia rosmarinus Spenn: Optimization of Anti-Wood-Decay Fungal Activity Using Mixture Design Methodology

Annemer S., Zoubi Y. E., Satrani B., Stambouli H., Assouguem A., Ullah R., ...Daha Fazla

ACS OMEGA, cilt.8, sa.30, ss.27030-27043, 2023 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 8 Sayı: 30
  • Basım Tarihi: 2023
  • Doi Numarası: 10.1021/acsomega.3c01970
  • Dergi Adı: ACS OMEGA
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Directory of Open Access Journals
  • Sayfa Sayıları: ss.27030-27043
  • Atatürk Üniversitesi Adresli: Evet

Özet

Chemical fungicides are often harmful to people and theenvironmentbecause of their toxicity. The wood protection industry places a highpriority on replacing them with natural products. Therefore, thisinvestigation focused on developing a formulation of a binary combinationof Salvia rosmarinus Spenn and Cedrus atlantica Manetti obtained by Simultaneoushydrodistillation to protect the wood from decay using a mixture designmethodology. The chemical composition of essential oil was identifiedby gas chromatography coupled with mass spectrometry (GC/MS), andtheir anti-wood-decay fungal activity was assessed using the macrodilutionmethod against four fungi responsible for wood decay: Coniophora puteana, Coriolus versicolor, Gloeophyllum trabeum, and Poria placenta. The results of GC/MS identified myrtenalas a new component appearing in all binary combinations. The optimumanti-wood-decay fungal activity was observed in a combination of 60% S. rosmarinus and 40% C. atlantica essential oils, providing an effective concentration for 50% ofmaximal effect (EC50) value of 9.91 & PLUSMN; 1.91 and 9.28 & PLUSMN; 1.55 & mu;g/mL for C. puteana and C. versicolor, respectively.The highest anti-wood-decay fungal activity for G.trabeum and P. placenta was found in the combination of 55% of S. rosmarinus and 45% of C. atlantica essentialoils, with EC50 values of 11.48 & PLUSMN; 3.73 and 22.619 & PLUSMN; 3.79 & mu;g/mL, respectively. Combined simultaneous hydrodistillationimproved the antifungal effect of these essential oils. These resultscould be used to improve antifungal activity and protect wood againstwood-decay fungi.