Alterations in Enzyme Activity of Carbonic Anhydrase, 6-phosphogluconate Dehydrogenase and Thioredoxin Reductase in Rats Exposed to Doxorubicin and Morin

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Aggul A. G., Kuzu M., Kandemir F. M., Küçükler S., Caglayan C.

CLINICAL AND EXPERIMENTAL HEALTH SCIENCES, cilt.10, sa.3, ss.228-234, 2020 (ESCI) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 10 Sayı: 3
  • Basım Tarihi: 2020
  • Doi Numarası: 10.33808/clinexphealthsci.632320
  • Dergi Adı: CLINICAL AND EXPERIMENTAL HEALTH SCIENCES
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.228-234
  • Anahtar Kelimeler: Doxorubicin, Morin, Carbonic Anhydrase, 6-phosphogluconate Dehydrogenase, Thioredoxin Reductase, INDUCED CARDIOTOXICITY, THERAPEUTIC APPLICATIONS, INDUCED APOPTOSIS, TOXICITY, METABOLISM, ACTIVATION, INHIBITORS, EXPRESSION, PROTECTION, PROFILES
  • Atatürk Üniversitesi Adresli: Evet

Özet

Objectives: Carbonic anhydrase (CA), 6-phosphogluconate dehydrogenase (6PGD) and thioredoxin reductase (TrxR) enzymes are the essential biological molecules needed for metabolic processes in all living cells. This study was designed to investigate the activities of CA, 6PGD and TrxR enzymes in the brain, kidney, liver, heart and testis tissues of the rats exposed to doxorubicin (DOX) and morin.