Bilateral ovarian ischemia/reperfusion injury and treatment options in rats with an induced model of diabetes

YAPÇA Ö. E., TURAN M. İ., BÖREKÇİ B., AKÇAY F., SÜLEYMAN H.

IRANIAN JOURNAL OF BASIC MEDICAL SCIENCES, cilt.17, sa.4, ss.294-302, 2014 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 17 Sayı: 4
  • Basım Tarihi: 2014
  • Dergi Adı: IRANIAN JOURNAL OF BASIC MEDICAL SCIENCES
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.294-302
  • Anahtar Kelimeler: Diabetes mellitus, Infertility, Injury, Ischemia/reperfusion, Ovary, Rat, ISCHEMIA-REPERFUSION INJURY, OXIDATIVE STRESS, SUPEROXIDE-DISMUTASE, NITRIC-OXIDE, MELATONIN, ACID, COMPLICATIONS, MELLITUS, TORSION, DAMAGE
  • Atatürk Üniversitesi Adresli: Evet

Özet

Objective(s): This study investigated the effects of melatonin, famotidine, mirtazapine, and thiamine pyrophosphate on ischemia/ reperfusion (I/ R) injury in diabetic rats and evaluated oxidant and antioxidant marker measurement results. It also examined the effects of the drugs aimed at preventing infertility that may result from I/ R injury.