Atatürk Üniversitesi Tıp Fakültesi Cerrahi Tıp Bilimleri Dergisi, cilt.1, sa.3, ss.73-79, 2022 (Hakemli Dergi)
Objectives: Although low levels of Vitamin D (VD) are considered an important risk factor in coronary artery disease (CAD)
due to its negative effects on vascular structures, the relationship between VD deficiency and postoperative complications of
coronary artery bypass grafting (CABG) operations is not clear. In present study, we aimed to investigate the relationship
between postoperative complications and VD levels in patients who underwent CABG. Methods: 150 patients who were
decided to have CABG operation and whose VD levels were measured in the preoperative period were included in the study.
The data were analyzed retrospectively, and 150 patients were divided into control group (Group A; 25-80 ng/mL) and VD
deficiency group (Group B; <25ng/mL) according to their VD levels. Preoperative, intraoperative and postoperative data were
recorded. Deaths within the first 30 days were accepted as mortality and morbidity during hospitalization were accepted as
complications. Results: Group A consisted of 75 patients (Male/Female; 53/22) with a VD level of 25-80 ng/mL and mean age
was 60.2±9.2 years, and Group B consisted of 75 patients (Male/Female; 48/27) with a VD value of <25 ng/mL and mean age
was 62.08±8.9 years. There was no difference between the groups in terms of gender (p=0.243), age (p=0.232), BMI (p=0.137),
and EuroScore (p=0.512). Mean of VD levels were 42.6±13.8 ng/mL in Group A and 10.08±5.7 ng/mL in Group B. (p<0.01)
Cardiopulmonary bypass (CPB; p=0.874) and aortic cross-clamp (ACC; p=0.495) times were longer in Group B. The number
of anatomoses was higher in Group A than Group B (3.27±0.79 and 2.80±0.88, respectively) (p=0.01) but the need for positive
inotropic support was higher in Group B patients. (p=0.03) The cumulative mortality rate was 3.3% (Group A/B:2/3).