Expression of hCA IX isoenzyme by using sumo fusion partner and examining the effects of antitumor drugs
TURKISH JOURNAL OF BIOCHEMISTRY-TURK BIYOKIMYA DERGISI, cilt.40, sa.4, ss.334-342, 2015 (SCI-Expanded, Scopus, TRDizin)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 40 Sayı: 4
- Basım Tarihi: 2015
- Doi Numarası: 10.1515/tjb-2015-0021
- Dergi Adı: TURKISH JOURNAL OF BIOCHEMISTRY-TURK BIYOKIMYA DERGISI
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
- Sayfa Sayıları: ss.334-342
- Anahtar Kelimeler: Cloning, expression, cancer, carbonic anhydrase IX, inhibition, CARBONIC-ANHYDRASE-IX, PROTEIN, HYPOXIA, TUMOR, PURIFICATION, BINDING, CANCER, MARKER, GENE
- Atatürk Üniversitesi Adresli: Evet
Özet
Objective: In this study, investigating the effects of inhibition of the enzyme activity of some antitumor drugs and the Cancer-Related Human Carbonic Anhydrase IX (hCA IX) isoenzyme expressing as a SUMO fusion protein in an Escherichia coli expression system were aimed.