Protective effects of telmisartan on ischemia/reperfusion injury of rat ovary: biochemical and histopathologic evaluation

KUMTEPE Y., Odabasoglu F., KARACA M., Polat B., Halici M. B., Keles O. N., ...Daha Fazla

FERTILITY AND STERILITY, cilt.93, sa.4, ss.1299-1307, 2010 (SCI-Expanded, Scopus)

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 93 Sayı: 4
  • Basım Tarihi: 2010
  • Doi Numarası: 10.1016/j.fertnstert.2008.12.016
  • Dergi Adı: FERTILITY AND STERILITY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.1299-1307
  • Anahtar Kelimeler: telmisartan, iNOS, ovarian, rat, torsion, ischemia, reperfusion, NITRIC-OXIDE SYNTHASE, ISCHEMIA-REPERFUSION INJURY, AT1-TYPE ANGIOTENSIN RECEPTOR, ENDOTHELIAL-CELLS, OXIDATIVE STRESS, BLOOD-PRESSURE, EXPRESSION, INTERLEUKIN-6, ANTAGONIST, ACTIVATION
  • Atatürk Üniversitesi Adresli: Evet

Özet

Objective: To evaluate the effects of telmisartan as an antioxidant and for its tissue protective properties and to study the biochemical and histopathologic changes in experimental ischemia and ischemia/reperfusion injuries in rat ovaries.