Efficacy of blood transfusion accompanied by antibiotics and B vitamins for the treatment of naturally occurring Leptospirosis in cattle

ÖZKANLAR Y., AKTAŞ M. S., KAYNAR Ö., ÖZKANLAR S., ÇELEBİ F.

REVUE DE MEDECINE VETERINAIRE, cilt.161, sa.7, ss.336-341, 2010 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 161 Sayı: 7
  • Basım Tarihi: 2010
  • Dergi Adı: REVUE DE MEDECINE VETERINAIRE
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.336-341
  • Atatürk Üniversitesi Adresli: Evet

Özet

In cattle with severe Leptospirosis, blood transfusion has not yet been evaluated as part of supportive treatment. The aim of this study was to determine the findings and to evaluate a whole blood transfusion as an adjunct to antibiotic and B vitamins in cattle with leptospirosis. Forty two cattle shedding urinary spirochetes and showing the clinical symptoms of Leptospirosis were randomly divided into two groups. L. Hardjo and L. Grippotyphosa were detected in 61.9% of serum samples by microscopic agglutination test. The cattle in group I (n=21) were administered dihydrostreptomycin-penicillin and vitamin B complex. The animals in group II (n=21) were given the same treatment, including a whole blood transfusion taken from healthy donors. Before the treatment, the mean values of erythrocytes. PCV, hemoglobin and platelets were low (P< 0.001), while MCV (P< 0.05) was high in both groups as compared to controls (n=10). The mean values of AST, ALT, ALP, GGT, BUN, creatinine and bilirubin were high (P< 0.001) in both groups. Twelve cattle in group I (57.1%) and 19 cattle in group II (90.5%) were survived by the treatments (P< 0.05). Thus, the administration of whole blood transfusion accompanied to antibiotics and vitamin B is rewarding in life-threatening cases.