Synthesis of bis(benzoxazole) frameworks chiralized by planar chiral [2.2]Paracyclophane
TETRAHEDRON LETTERS, 2021 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Basım Tarihi: 2021
- Doi Numarası: 10.1016/j.tetlet.2021.152871
- Dergi Adı: TETRAHEDRON LETTERS
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, Aquatic Science & Fisheries Abstracts (ASFA), BIOSIS, Biotechnology Research Abstracts, CAB Abstracts, Chemical Abstracts Core, Chimica, EMBASE, Veterinary Science Database, Index Chemicus (IC)
- Anahtar Kelimeler: Bis(benzoxazole), [2.2]Paracyclophane, Planar chirality, Horeau principle
- Atatürk Üniversitesi Adresli: Evet
Özet
In this study, a new class of chiral bis(benzoxazole) has been synthesized. The bis(benzoxazole) framework, which has an achiral structure was chiralized by a planar chiral [2.2]paracyclophane moiety. Both enantiomeric forms of the bis(benzoxazole) derivatives were successfully obtained in 99% ee. Even though the starting material was not completely enantiomerically pure, enantiomeric enrichment was afforded by the Horeau principle in the synthesis route. (C) 2021 Elsevier Ltd. All rights reserved.