The association of human leukocyte antigenpolymorphisms with disease severity and latencyperiod in patients with silicosis


Doğan H., Akgün M., Araz Ö., Yılmazel Uçar E., Yörük Ö., Balkan E., ...Daha Fazla

Multidisciplinary Respiratory Medicine, cilt.9, ss.1-6, 2014 (ESCI) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 9
  • Basım Tarihi: 2014
  • Doi Numarası: 10.1186/2049-6958-9-17
  • Dergi Adı: Multidisciplinary Respiratory Medicine
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus
  • Sayfa Sayıları: ss.1-6
  • Anahtar Kelimeler: HLA polymorphism, Immunity, Latency, Severity, Silicosis
  • Atatürk Üniversitesi Adresli: Evet

Özet

Background: Denim sandblasting may cause silicosis as a result of free crystalline silica inhalation. Its pathogenesis remains unclear, but autoimmunity may play a role in the development of silicosis. The present study aimed to investigate the relationships between human leukocyte antigen (HLA) and the severity and latency period of silicosis.