The association of human leukocyte antigenpolymorphisms with disease severity and latencyperiod in patients with silicosis

Doğan, Hasan; Akgün, Metin; Araz, Ömer; Yılmazel Uçar, Elif; Yörük, Özgür; Balkan, Eda; Atış, Ömer; Akdemir, Fatih; Acemoğlu, Hamit; Pirim, İbrahim

doi:10.1186/2049-6958-9-17

The association of human leukocyte antigenpolymorphisms with disease severity and latencyperiod in patients with silicosis

Doğan H., Akgün M., Araz Ö., Yılmazel Uçar E., Yörük Ö., Balkan E., ...Daha Fazla

Multidisciplinary Respiratory Medicine, cilt.9, ss.1-6, 2014 (ESCI, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 9
Basım Tarihi: 2014
Doi Numarası: 10.1186/2049-6958-9-17
Dergi Adı: Multidisciplinary Respiratory Medicine
Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus
Sayfa Sayıları: ss.1-6
Anahtar Kelimeler: HLA polymorphism, Immunity, Latency, Severity, Silicosis
Atatürk Üniversitesi Adresli: Evet

Özet

Background: Denim sandblasting may cause silicosis as a result of free crystalline silica inhalation. Its pathogenesis remains unclear, but autoimmunity may play a role in the development of silicosis. The present study aimed to investigate the relationships between human leukocyte antigen (HLA) and the severity and latency period of silicosis.