Thrombotic thrombocytopenic purpura in a patient with brucella infection is highly responsive to combined plasma infusion and antimicrobial therapy
MEDICAL PRINCIPLES AND PRACTICE, cilt.16, sa.4, ss.324-326, 2007 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 16 Sayı: 4
- Basım Tarihi: 2007
- Doi Numarası: 10.1159/000102159
- Dergi Adı: MEDICAL PRINCIPLES AND PRACTICE
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.324-326
- Anahtar Kelimeler: thrombotic thrombocytopenic purpura, brucellosis, antimicrobial treatment
- Atatürk Üniversitesi Adresli: Evet
Özet
Objective: To report a case of brucella infection presenting with thrombotic thrombocytopenic purpura (TTP) that responded well to plasma and antimicrobial treatment infusion. Case Presentation and Intervention: A 51-year-old man with moderate confusion, depressed mood and dysarthria was admitted. He was chronically ill, with fever (38.5 degrees C), anemia, jaundice and petechial-purpuric skin lesions. Neurological examination revealed diminished consciousness with a Glasgow coma scale score of 7 and +1 neck rigidity. The hemoglobin and platelet counts were decreased and reticulocyte index, erythrocyte sedimentation rate, as well as serum lactate dehydrogenase and renal dysfunction were elevated. TTP was a possible diagnosis and the patient responded well to plasma infusion and antimicrobial treatment. Conclusion: This report shows that therapy of underlying infection together with plasma infusion may be a successful treatment option for brucellosis-induced TTP. Copyright (C) 2007 S. Karger AG, Basel.