Evaluation Expression of the Caspase-3 and Caspase-9 Apoptotic Genes in Schizophrenia Patients

Dirican, Ebubekir; ÖZCAN, Halil; Uzuncakmak, Sevgi; TAKIM, Uğur

doi:10.9758/cpn.2023.21.1.171pissn1738-1088/eissn2093-4327

Evaluation Expression of the Caspase-3 and Caspase-9 Apoptotic Genes in Schizophrenia Patients

Dirican E., ÖZCAN H., Uzuncakmak S. K., TAKIM U.

CLINICAL PSYCHOPHARMACOLOGY AND NEUROSCIENCE, cilt.21, sa.2, ss.171-178, 2023 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 21 Sayı: 2
Basım Tarihi: 2023
Doi Numarası: 10.9758/cpn.2023.21.1.171pissn1738-1088/eissn2093-4327
Dergi Adı: CLINICAL PSYCHOPHARMACOLOGY AND NEUROSCIENCE
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, BIOSIS, EMBASE, Psycinfo
Sayfa Sayıları: ss.171-178
Anahtar Kelimeler: Schizophrenia, Apoptosis, Caspase-3, Caspase-9, Real time PCR, Intrinsic pathway, BCL-2, BAX, EVENTS, STRESS, DEATH, LIFE
Atatürk Üniversitesi Adresli: Evet

Özet

Objective: Apoptosis is programmed cell death that occurs by several pathways. Caspase-3 is induced by active caspase-9 via the intrinsic pathway. The aim of this research was to explore the expression of caspase-3 and caspase-9 in schizophrenia patients and healthy samples.