Türkiye Klinikleri Diş Hekimliği Bilimleri Dergisi, cilt.27, sa.4, ss.704-709, 2021 (Hakemli Dergi)
ABSTRACT
Low grade
tubulopapillary adenocarcinoma is one of the rare sinonasal tumors. A
65-year-old male patient was admitted to our clinic with painless intraoral and
extraoral swelling and speech disorder. Radiological examination of
the patient revealed a lesion suggesting malignancy. The area of the lesion
spread from the left maxillary area to the maxillary sinus, nasal cavity,
zygomatic bone and the base of the eye, causing resorption of the bones in the
regions. As a result of biopsy, the lesion was diagnosed as well-differentiated
low-grade tubulopapillary adenocarcinoma. The patient was referred to the
oncology department of the medical faculty and the radiotherapy was started by
the medical faculty board, indicating that it was not suitable for surgical
treatment. After 1.5-year follow-up, the patient was re-biopsied and diagnosed
as poorly differentiated tubulopapillary adenocarcinoma. We think that the
aggressive lesion may show heterogeneous differentiation as a possible reason
for the differentiation between the two biopsies.
Keywords: low grade tubulopapillary adenocarcinoma; sinonasal
tumors; ultrasonography; magnetic resonance imaging