Akademik Veri Yönetim Sistemi
6th INTERNATIONAL CONFERENCE ON GLOBAL PRACTICE OF MULTIDISCIPLINARY SCIENTIFIC STUDIES , Lisbon, Portekiz, 9 - 16 Nisan 2024, ss.204, (Özet Bildiri)
Voriconazole is an antifungal medication effective against fungal infections and is often used to treat serious infections such as systemic fungal infections. Voriconazole belongs to the triazole class of antifungal drugs and, by its chemical structure, aims to control infections by inhibiting the growth and proliferation of fungal cells. Voriconazole is commonly used to treat serious fungal infections, especially aspergillosis. It is also effective in treating invasive candidiasis and other fungal infections. Voriconazole may also be used in the prophylactic treatment of patients with immunodeficiency conditions. In the literature review, studies on the quantity determination of voriconazole in pharmaceutical preparations were found. Changing industry technologies and quality control needs increase the need for faster, reliable and repeatable analytical methods in the analysis of pharmaceutical active ingredients. The aim of this study is to develop methods different from the methods in the literature for the quantification of the active ingredient Voriconazole in pharmaceutical preparations, to validate them, and at the same time to show that these methods can be applied by making quantification in pharmaceutical preparations containing the active ingredient Voriconazole.This study aims to analyze voriconazole in pharmaceutical preparations using the assisted UV-visible spectrophotometry method. Voriconazole is a triazole antifungal agent effective in the treatment of invasive fungal infections. This study aims to develop an analytical technique that will allow voriconazole to be measured in a simple and cost-effective manner. The method is based on the reduction of voriconazole by reaction with thionine under alkaline conditions.