ACTA MEDICA MEDITERRANEA, cilt.31, sa.1, ss.115-120, 2015 (SCI-Expanded)
Introduction: Some chronic inflammatory or autoimmune conditions and various cutaneous granulomatous disorders are associated with an increased occurrence of malignancies. Human HIV-1 TAT-Interactive Protein 2 (HTATIP2/TIP30), also called TIP30 or CC3, is expressed in human tissues and some tumor tissues. Therefore, HTATIP2/TIP30 can be a possible target for early diagnosis, prediction of prognosis, and/or treatment of rheumatoid arthritis (RA), ankylosing spondylitis (AS) and sarcoidosis co-morbid malignancies.