Investigation of the Effects of Pregnenolone on Behavioral Tests Against Cisplatin-Induced Toxicity in Rats


Hacımüftüoğlu A., Okkay U.

TNED 2020, İstanbul, Türkiye, 26 - 28 Kasım 2020, ss.40-41

  • Yayın Türü: Bildiri / Tam Metin Bildiri
  • Basıldığı Şehir: İstanbul
  • Basıldığı Ülke: Türkiye
  • Sayfa Sayıları: ss.40-41
  • Atatürk Üniversitesi Adresli: Evet

Özet

The neurosteroid pregnenolone is potent endogenous neuromodulator and has various actions in the central nervous system. Although pregnenolone has particular roles in brain functions, including effects on cognition, emotion, motivation and motor skill, the exact mechanism of pregnenolone action is not clear. The aim of this study was to investigate behavioral effects of pregnenolone using an animal model of cisplatin toxicity