Peritonitis Incidence is Correlated with Increased Leptin and CD4/CD8 Ratio in Peritoneal Dialysis Patients

Bilen, Yusuf; ÇANKAYA, Erdem; Bilen, Nurhan; UYANIK, Abdullah; ERDEM, Fuat; UYANIK, Muhammet

doi:10.5262/tndt.2015.1003.10

Peritonitis Incidence is Correlated with Increased Leptin and CD4/CD8 Ratio in Peritoneal Dialysis Patients

Bilen Y., ÇANKAYA E., Bilen N., UYANIK A., ERDEM F., UYANIK M. H.

TURKISH NEPHROLOGY DIALYSIS AND TRANSPLANTATION JOURNAL, cilt.24, sa.3, ss.307-311, 2015 (ESCI, Scopus, TRDizin)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 24 Sayı: 3
Basım Tarihi: 2015
Doi Numarası: 10.5262/tndt.2015.1003.10
Dergi Adı: TURKISH NEPHROLOGY DIALYSIS AND TRANSPLANTATION JOURNAL
Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus, TR DİZİN (ULAKBİM)
Sayfa Sayıları: ss.307-311
Atatürk Üniversitesi Adresli: Evet

Özet

Peritonitis is one of the leading cause of hospitalization in peritoneal dialysis patients. Although inflammatory markers show an increased inflammatory response, cellular immune response is decreased in ESRD patients. Uremia has many affects on leptin and T lymphocytes that are basic elements of the cellular immune system. In this study, we aimed to demonstrate the relationship between peritonitis and the CD4, CD8 positive lymphocyte count and ratio, and serum leptin level in peritoneal dialysis patients.