Akademik Veri Yönetim Sistemi
Green Sustainable Process for Chemical and Environmental Engineering and Science, Inamuddin,Charles Oluwaseun Adetunji,Abdullah M. Asiri, Editör, Elsevier Science, Oxford/Amsterdam , Amsterdam, ss.347-365, 2021
Biosurfactants are surface-active amphiphilic compounds produced mostly on microbial cell surfaces or excreted extracellularly. Because of their ability to reduce surface and interface tension, biosurfactants have been used as emulsifiers, wetting agents, dispersing agents, detergents, and foaming agents and therefore have received more attention recently. The main concerns in using biosurfactants as an alternative to synthetic counterparts are high production costs and low yields. Many application areas, such as bioremediation and oil recovery, require large quantities of biosurfactants. Accordingly, the production process must be efficient and economical. Improving the production process relies on many strategies such as the use of inexpensive raw materials, optimization of cultivation conditions, and screening for overexpressing strains. Yet, the most important point is to scale-up the production by using bioreactors.
Efficient scale-up from laboratory to industrial production requires compliance with some parameters. The most prominent parameters for efficient microbial growth and biosurfactant production are the choice of high-yielding microorganisms, adequate inoculum size, cheap carbon and nitrogen sources, and appropriate C/N ratio in the medium. Sufficient aeration and agitation, favorable temperature and pH controls, use of antifoaming agents are other crucial factors affecting the overall yield of biosurfactant production in bioreactors.