Clinical importance of asymmetry and handedness differences in common carotid artery intima-media thickness

ONBAS O., DANE S., Kantarci M., KOPLAY M., Alper F., Okur A.

INTERNATIONAL JOURNAL OF NEUROSCIENCE, cilt.117, sa.4, ss.433-441, 2007 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 117 Sayı: 4
  • Basım Tarihi: 2007
  • Doi Numarası: 10.1080/00207450600592230
  • Dergi Adı: INTERNATIONAL JOURNAL OF NEUROSCIENCE
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.433-441
  • Anahtar Kelimeler: asymmetry, atherosclerosis, carotid arteries, handedness, ultrasonography, IMMUNE HYPERSENSITIVITY, MYOCARDIAL-INFARCTION, HERPES-ZOSTER, RISK, ATHEROSCLEROSIS, SIDE, DISEASE, INNATE, STROKE, PLAQUE
  • Atatürk Üniversitesi Adresli: Evet

Özet

Earlier publications have reported that common carotid artery intima-media thickness (CCA-IMT) was lower on the right side than on the left side and that left-handed patients have a lower risk of sudden death of brain infarction. This study aimed to determine whether there is an asymmetry and the handedness related difference in CCA-IMT. Ultrasonographic examinations were performed with the use of Aplio US system. In total sample, male and female left-handers, CCA-IMT was greater on left side than on right side. In men, both right and left CCA-IMTs, but in women only right IMT, were lower in the left-handers than in the right-handers. Both right and left CCA-IMTs was positively correlated with age in men and in women. Handedness was a significant factor influencing CCA-IMT with adjustment for sex and age. It was greater on left side than on right side, especially in the left-handers. CCA-IMTs were lower in the left-handers than in the right-handers. These results suggest that hemodynamic stress and intimal damage was larger in the left carotid artery, which was larger in the right-handers compared to the left-handers.