Association between hepatic alveolar echinococcosis and frequency of human leukocyte antigen class I and II alleles in Turkish patients

Aydınlı B., Pirim I., Polat K. Y., Gursan N., Atamanalp S. S., Ezer M., ...Daha Fazla

HEPATOLOGY RESEARCH, cilt.37, sa.10, ss.806-810, 2007 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 37 Sayı: 10
  • Basım Tarihi: 2007
  • Doi Numarası: 10.1111/j.1872-034x.2007.00137.x
  • Dergi Adı: HEPATOLOGY RESEARCH
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.806-810
  • Atatürk Üniversitesi Adresli: Evet

Özet

Background: Human alveolar echinococcosis (AE) is a potentially fatal, chronically progressive hepatic infestation that is characterized by a long asymptomatic period in which an invasive tumor-like lesion develops. Several studies have suggested that genetic susceptibility to AE may be linked to HLA class II alleles. We investigated the association between AE and antigen HLA-A, B, C, DR and DQ profiles of patients with hepatic AE (HAE) in the eastern part of Turkey.